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Papaya, Dengue fever and Ayurveda

P. Ram Manohar
Director and Chief Scientific Officer, AVP Research Foundation, Coimbatore, Tamil Nadu, India E-mail: gro.hcraeserpva@osc
Copyright : © Ancient Science of Life

1. One study found that the papaya seed was toxic to the Aedes aegypti mosquito, which is a vector for the etiologic agents of both yellow and dengue fever.[1]
2. Another study reported that in in vitro models, papaya leaves demonstrated significant inhibition of hemolysis.[2]
3. A third study in mice revealed significant increase in thrombocyte counts compared to the controls.[3]
4. There is one clinical study, which is a randomized controlled trial in 228 patients that reported significant increase in platelet production in patients with dengue and dengue hemorrhagic fever after administration of papaya leaves.[4]
5. The fifth study is a case report on a single patient with dengue fever showing significant increase in platelet count after administration of papaya leaves.[5]

References
1. Nunes NN, Santana LA, Sampaio MU, Lemos FJ, Oliva ML. The component of Carica papaya seed toxic to A. Aegypti and the identification of tegupain, the enzyme that generates it. Chemosphere. 2013;92:413–20. [PubMed: 23402920]
2. Ranasinghe P, Ranasinghe P, Abeysekera WP, Premakumara GA, Perera YS, Gurugama P, et al. In vitro erythrocyte membrane stabilization properties of Carica papaya L. leaf extracts. Pharmacognosy Res. 2012;4:196–202. [PMCID: PMC3510871] [PubMed: 23225962]
3. Sathasivam K, Ramanathan S, Mansor SM, Haris MR, Wernsdorfer WH. Thrombocyte counts in mice after the administration of papaya leaf suspension. Wien Klin Wochenschr. 2009;121(Suppl 3):19–22. [PubMed: 19915811]
4. Subenthiran S, Choon TC, Cheong KC, Thayan R, Teck MB, Muniandy PK, et al. Carica papaya leaves juice significantly accelerates the rate of increase in platelet count among patients with dengue fever and dengue haemorrhagic fever. Evid Based Complement Alternat Med 2013. 2013 616737. [PMCID: PMC3638585]
5. Ahmad N, Fazal H, Ayaz M, Abbasi BH, Mohammad I, Fazal L. Dengue fever treatment with Carica papaya leaves extracts. Asian Pac J Trop Biomed. 2011;1:330–3. [PMCID: PMC3614241] [PubMed: 23569787]

Treatment & Management of Dengue (DANDAKA JWARA) with Ayurveda  
Management
• Punarnava (Borhavia diffusa) Is a herb which helps in flushing out toxins through perspiration.
• Amrithotharam kashayam, Amritha satva (Sat giloy) are some of the good herbal medicines advised in Dengue fever.
• Boil tulasi in water and drink this water throughout the day to build up immune system.
• Dhatura is an Ayurvedic herb which has potency to reduce seriousness of dengue fever, but should be strictly taken after consulting Ayurvedic physician.

Amrita (Guduchi), Tulasi (Holi basil), Shunthi (Dried ginger), Papaya  are the commonly available medicinal plants and used to prevent its complications by potentiating immune system so that disease gets controlled within a  period of 4to 8 days.

Diet During Dandaka jvara 
Rice gruel (Kanji),Rice porridge (khichari) cooked with ginger and lemon  is useful.
Tea prepared with Tulasi, Ginger and cardamom may be taken at two hourly interval.
Spicy and Oily food should be strictly avoided.
Pomegranate /black grape juice can be taken to increase blood count

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